Plant-derived products are now gaining recognition worldwide currently recommended for primary healthcare, but only a few plants have received rigorous scientific investigation. Herbal drugs are the potential source of various plant constituents which are responsible for the prevention and treatment of a range of diseases. The present work mainly summarizes the evaluation of antimalarial activity of medicinal plants by various researchers. This helps in decisive objective of finding narrative anti-malarial compounds, which can be used in the struggle against drug-resistant malaria. Moreover, the use of new technologies and methodologies in accordance with sound scientific ideology is encouraged.