Navneet Kumar Verma, Asheesh Kumar Singh, Prem Chand Mall, Vikas Yadav
Lornoxicam is a non-steroidal anti-inflammatory drug of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. It is available in oral and parenteral formulations. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that particularly explains the pronounced efficacy of the drug. Lornoxicam's anti-inflammatory and analgesic activity is related to its inhibitory action on prostaglandin and thromboxane synthesis through the inhibition of both COX-1 and COX-2. This leads to the reduction of inflammation, pain, fever, and swelling, which are mediated by prostaglandins. However, the exact mechanism of lornoxicam, like that of the other Non-steroidal anti-inflammatory drugs (NSAIDs), has not been fully determined. In this article authors had discuss about the preformulation study.
Navneet Kumar Verma, Asheesh Kumar Singh, Prem Chand Mall, Vikas Yadav. Identification and characterisation of lornoxicam (non-steroidal anti-inflammatory drug). Int. J. Pharm. Clin. Res. 2019;1(2):01-03.