International Journal of Pharmaceutical and Clinical Research

International Journal of Pharmaceutical and Clinical Research

Vol. 1, Issue 2, Part A (2019)

Identification and characterisation of lornoxicam (non-steroidal anti-inflammatory drug)

Author(s):

Navneet Kumar Verma, Asheesh Kumar Singh, Prem Chand Mall, Vikas Yadav

Abstract:
Lornoxicam is a non-steroidal anti-inflammatory drug of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. It is available in oral and parenteral formulations. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that particularly explains the pronounced efficacy of the drug. Lornoxicam's anti-inflammatory and analgesic activity is related to its inhibitory action on prostaglandin and thromboxane synthesis through the inhibition of both COX-1 and COX-2. This leads to the reduction of inflammation, pain, fever, and swelling, which are mediated by prostaglandins. However, the exact mechanism of lornoxicam, like that of the other Non-steroidal anti-inflammatory drugs (NSAIDs), has not been fully determined. In this article authors had discuss about the preformulation study.

Pages: 01-03  |  1043 Views  521 Downloads

How to cite this article:
Navneet Kumar Verma, Asheesh Kumar Singh, Prem Chand Mall, Vikas Yadav. Identification and characterisation of lornoxicam (non-steroidal anti-inflammatory drug). Int. J. Pharm. Clin. Res. 2019;1(2):01-03.