Vol. 5, Issue 1, Part A (2023)

Acenocoumarol is an Vitamin K Antagonist used for Deep vein thrombosis, Heart valve replacement, Atrial fibrillation and increase the risk of bleeding. we report a Case of 47 year old patient presented with symptoms of redness in right eye and had a history of aortic valve replacement and taking Acitrom drug. On the basis of elevated PT/INR the patient was diagnosed as drug induced coagulopathy. The causality assessment was done according to WHO – UMC Scale and identified ADR was certain. A treatment regimen include withheld the drug and Vitamin K was administered. After the revision of PT / INR acenocoumarol was re-administered with low dose. The Patient need routine monitoring of PT / INR to counteract the risk of adverse effects.