Photodynamic therapy (PDT) is a cancer and infectious illness therapy that uses reactive oxygen species (ROS) are produced by light and a photosensitizer to cause cellular damage. In this review, we focus on recent advancements of PDT and how they may be manipulated to improve clinical outcome in cancer patients. PDT has demonstrated a promising translation into cancer therapeutics when combined with chemotherapy, PTT and immunotherapy. Additionally, PDT is being used to treat bacterial infections in order to combat antibiotic resistance. We have now covered the new paths PDT is taking in the treatment of infectious and cancerous disorders. In summary, we think that the development of PDT for cancer may be greatly influenced by advancements in nanomaterials and thoughtful design.
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