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International Journal of Pharmaceutical and Clinical Research
Peer Reviewed Journal

Vol. 7, Issue 1, Part A (2025)

A comprehensive review of anticancer drug therapy: Advances and challenges

Author(s):

Sameer Abed Mohammed, Ammar Jawad Kadhim and Mohanad Salam Hussein

Abstract:

This review provides an overview of anticancer drug therapies, including their classifications, mechanism of action, and the evolution of treatment modalities. The review emphasizes the transition from traditional chemotherapeutic agents to targeted therapies with traditional chemotherapeutic agents, targeted therapies, immunotherapies, monoclonal antibodies, tyrosine kinase inhibitors, hormone therapies, and novel methods like CAR-T cell therapy and nanotechnology delivery systems. Anticancer drugs act through induce DNA damage, the role modulation of the cell cycle, inhibition of tumor.angiogenesis Despite of advancements in nextgeneration sequencing, To overcome these challenges, diverse strategies, including drug resistance and appropriate dosage, dosing and targeting to gain the benefit with minimal harm to the person through treatment. Anticancer drug delivery systems (DDS) and identifies new developments in strategies of molecular targeting and advances in drug delivery system. Advancements in personalized drug development, focusing on genomic profiling of tumors play role important to give better treatment and overcome of difficulties in cancer therapy. The reviews existing evidence on current innovative efforts and make modern treatment options more equally accessible to improve patient outcomes lives.

Pages: 01-09  |  993 Views  446 Downloads


International Journal of Pharmaceutical and Clinical Research
How to cite this article:
Sameer Abed Mohammed, Ammar Jawad Kadhim and Mohanad Salam Hussein. A comprehensive review of anticancer drug therapy: Advances and challenges. Int. J. Pharm. Clin. Res. 2025;7(1):01-09. DOI: 10.33545/26647591.2025.v7.i1a.115
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